Randstad, as the EMEA Johnson & Johnson talent acquisition partner, is responsible for finding and contracting talent for the contingent roles at Johnson & Johnson. If you are selected for a role you will be engaged or employed by one of the Randstad recruitment companies in EMEA and will not be an employee of Johnson & Johnson.

Johnson & Johnson

BE - Research and Development Scientist

Posted Apr 22, 2021
Job ID: JJJP00006398
Location
Beerse
Duration
1 year
(May 10, 2021 - Apr 30, 2022)
Hours/week
40 hrs/week
Payrate range
Unknown

Johnson & Johnson Worksense (via Randstad Sourceright) is responsible for finding, engaging and contracting talent for the Johnson & Johnson contingent workforce.

 

At our Janssen Research and Development site in Beerse, Belgium we have a temporary position for a motivated individual with a strong ability to connect, to deliver on goals and objectives, foster an environment of collaboration, collegiality, and positive communication. Candidates will have to work in the context of a multidisciplinary, global, geographically disperse team.


The Structural & Protein Sciences department is responsible for the delivery of proteins to enable assay development, HTS, pharmacological profiling and structural biology (X-ray crystallography, Cryo-EM and NMR). The Protein Science Team collaborates closely with Janssen Therapeutic Areas and functional teams and with external collaborators in academia and industry.


Responsibilities:

  • Support protein production from small-scale expression testing to upscaling and protein purification and quality control analysis of produced proteins for H2L and LO activities in the different projects.
  • Majority (90 %) of time will be hands-on work in the laboratory.
  • Perform protein expression in bacteria, yeast, baculovirus / insect cells and mammalian systems to support the purification of proteins for screening, crystallography and assay development.
  • Purify proteins using different types of chromatography (affinity, ion exchange, size exclusion) on Akta equipment.
  • Test innovative approaches to protein production including evaluation of new technologies.
  • Perform quality control on produced proteins.
  • Analyze, interpret, summarize and report experimental data. Maintain accurate records (electronic notebook). Write and update protocols and reports.
  • Present results and conclusions at internal team meetings.
  • Assist or take responsibility for various tasks such as shipping logistics, database entry of externally produced reagents, maintenance of cell lines, etc.
  • Review reports for accuracy and completeness.
  • Communicate effectively with investigational staff, team members and functional manager.
  • Work under limited supervision with a high level of autonomy.
  • Positive attitude, enthusiastic and motivated.
  • Strictly adhere to local safety regulations and laboratory rules.


Qualifications:

  • Bachelor, Master or PhD degree in Biology, Biochemistry, Pharmaceutical Science, ...
  • 2 or more years industry experience is preferred.
  • Experience in recombinant expression of proteins in various heterologous systems (E. coli bacteria, insect cells, mammalian cell lines, cell-free systems) is required.
  • Expertise in the purification of high-quality proteins using standard techniques and equipment (affinity, ion exchange, size exclusion chromatography via FPLC, SDS-PAGE, Westerns) is required.
  • Expertise in protein characterization using techniques such as analytical gel filtration, mass spectrometry, dynamic light scattering, nano DSF, SPR is preferred.
  • Experience in protein construct design is preferred.
  • Knowledge of protein crystallization and structure determination is a plus


EXTRA INFORMATION:

  • Flexible working hours.
  • This is a contracting position, with the possibility of an extension after the end date. You will receive a contract via our partner Ausy. Ausy can offer you a contract of indefinite duration or a project contract for the duration of the assignment at J&J.


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