Scientist

Scientist 

Location: Beerse  

Hours: 40 hours, onsite - 12 months contract role

Essential: Responsible for the execution of lab-based experiments to support the validation of targets and preclinical drug discovery projects - include designing, implementing, monitoring and analyzing in vivo and in vitro experimental work. 

The Role:

The scientist is part of a dynamic, multi-disciplinary team in exploratory immuno-oncology, playing a key role in the evaluation and understanding of new drug concepts in vivo. The experienced scientist is responsible for the execution of lab-based experiments to support the validation of targets and preclinical drug discovery projects. In detail, responsibilities include designing, implementing, monitoring and analyzing in vivo and in vitro experimental work. 

This position requires hands-on expertise in mouse handling, immunological techniques including ELISA/ MSD/Luminex and experience with sterile cell culture and manipulation. Furthermore, the scientist is responsible for the independent execution of experiments, analysis of results and graphical data representation. 

Key Responsibilities:

• Experienced with hands-on animal handling in oncology-relevant rodent models such as subcutaneous and orthotopic tumor implantation techniques and dosing, proper handling of therapeutics, tumor measurement, health monitoring, and data collection and analysis.

• Experience in cell culture work

• Experience in the isolation and analysis of cells/tissue/blood/plasma/serum using flow cytometry or immunoassays (ELISA/MSD/Luminex) is a plus.

• Efficient managing and planning of multiple experiments 

• Performs data analysis and interpretation

• Collaborating with scientists in multiple disciplines

• Excellent compliance level with Electronic Lab Notebook reporting (ELN) and Environmental Health and Safety regulations (EHS)

• Fluent in written and spoken English

• Experience with Microsoft Office Excel, Word, Studylog, FACS analysis software, statistical and graphical analysis software

• This position may require occasional weekend, evening, and holiday dosing/animal monitoring.

Major Duties & Responsibilities

• In order of importance, briefly describe, in sentence form, the essential functions/major responsibilities of this position (principal duties and responsibilities of the position) as it exists today.  Describe the job, not the person in the job.  Each item listed below should be an essential function/major responsibility of the position, not a day-to-day activity.

• Typically, job descriptions should contain no more than seven or eight major responsibilities ranked in order of highest percentage time to least.

Tasks/Duties/Responsibilities

• 65% Experimental lab work includes but is not limited to in vivo rodent handling, dosing, tumor implantation, tumor volume measurement, collection and analysis of cells/tissue/blood/plasma/serum/supernatant using flow cytometry, ELISA/MSD/Luminex

• 10% Analysis of data and graphical representation, literature searches to confirm data

• 15% Drafting protocol - Signals reporting

• 5% Maintenance of cell cultures

• 5%  Meetings with the extended team, colleagues, supervisor, …

Other Duties

Smaller day-to-day tasks or infrequent tasks: lab cleaning, supply inventory keeping, following appropriate trainings, unpacking orders and shipments,

Required Education:    

Master degree in Biomedical Sciences, Biotechnology, Biology or Genetic Engineering or other or equivalent through relevant experience in a laboratory environment.   

Required Knowledge, Skills and Abilities: 

Experienced in vivo rodent handling, dosing, tumor implantation, tumor volume measurement, sample collection and analysis of cells/tissue/blood/plasma/serum/supernatant using flow cytometry, ELISA/MSD/Luminex, Immunohistochemistry. Cell line culture techniques required. Graphpad skills for statistical analysis and graphical representation. 

Excellent organizational skills, experimental documentation, and a proven ability to work collaboratively in a fast paced, highly matrixed, interactive environment is essential.  

Strong communication and reporting skills (good knowledge of English is required)

Basic MS Office programs (powerpoint, word, excel, ….) 

Preferred Qualifications

• Consider and identify qualifications that are not required to perform the job but would be very helpful to performing the job.

• Preferred Minimum Education:  Master degree in Biomedical Sciences, Biotechnology, Biology or Genetic Engineering.

• Preferred Area of Study:  A background in immunology and oncology is a plus.